MELATONIN AND MITOCHONDRIA
Mitrochondria are implicated in apoptosis.
Melatonin (N-acetyl-5-methoxytryptamine) has the capacity to reduce apoptosis programs (cancer) and to enhance apoptosis programs (worsen neurodegenerative and ischemic conditions).
scavenges oxygen and nitrogen based reactants in the mitochondria, thus limiting the loss of intramitochondrial glutathione
lowers mitochondrial protein damage
improves electron transport chain activity
reduces mitrochondrial DNA damage
improves mitochondrial respiration
increases ATP synthesis